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Centers for Disease Control and Prevention to determine the prescription painkiller overdose death rate for each state between 1999 and 2010, and then took into account whether and when each hermes belt outlet state had passed a medical marijuana hermes bags law.Overdose deaths from prescription painkillers have skyrocketed over the past two decades, increasing 118 percent between 1999 and 2011, according to the CDC.The agency estimates that every day 113 people die from drug overdoses in the United States, and another 6,700 land in the emergency room from an overdose.Currently, 23 states allow medical marijuana to ease chronic pain and other conditions.The researchers reviewed death certificates from all states between 1999 and 2010, when 13 states had legalized marijuana.While overdose deaths have risen in all states, Bachhuber and hermes bags replica his colleagues found that the annual average number of deaths caused by painkillers is nearly 25 percent less in states with medical marijuana laws."In absolute terms, states with a medical marijuana law had about 1,700 fewer opioid painkiller overdose deaths in 2010 than would be expected based on trends hermes purse before the laws were passed," Bachhuber said.States' overdose death rates decline an average 20 percent in the first year following the passage of a medical marijuana law, the researchers found. By the second year, overdose death rates on average decline 25 percent, and as much as 33 percent by five years after legalization of medical pot.Medical marijuana laws also are associated with a more dramatic decrease in overdose death rates than other means commonly used to tackle prescription drug hermes birkin sale abuse, the study noted.For example, prescription drug monitoring programs are associated with an average hermes handbags 3.7 percent increase in overdose deaths, compared with a 24.8 percent decline associated with medical pot legalization, according to the study.Bachhuber cautioned that the exact mechanism underlying these study results is unclear, and that the findings don't prove a direct cause and effect relationship between medical marijuana laws and overdose deaths.Flansbaum agreed. Although he called the paper "provocative" and "stimulating," he said it doesn't prove that medical marijuana reduces drug overdoses."There are so many things going on in states, whether it be cultural or through laws, it's hard to say what's the effect of the medical marijuana law versus everything else that's happening," Flansbaum said.